Uywihug was an extremely powerful entity that ruled over vast parts of The Nested Infinity. It got destroyed by The Seeker, because Uywihug was getting too much power.
Uywihug was created from a huge collection of Omniverses of Reality by previous Panomni-gods. The Panomni-gods were desperate to keep their Nested Infinity under control, since there were Omni-Gods that didn't follow the them, and were casuing havoc everywhere. When Uywihug was created, it immediately subdued every single rebellion and Omni-God and destroyed all of them. It later destroyed most of the other Panomni-gods in the Nested Infinity. Uywihug became a sort of "tyrant" and controlled every single verse, reality, and even void in the entire Nested Infinity.
That caused The Seeker to destroy Uywihug. The Nested Infinity was slowly rebuilt afterwards.